Catallaxy crowdsource – Ivermectin

Posted on August 6, 2021 by Adam D

The most recent google result for ivermectin was from a site called “the scientist” with a post titled – Ivermectin (still) lacks scientific support as a covid-19 drug.

I won’t do the honour of linking to it but to see such disinformation in such trying times is disheartening.

Nonetheless we must persevere and I am currently piecing together a history of Ivermectin in relation to covid-19. The goal is to have something persuasive enough to improve the discussion around the topic. Perhaps if we can get it shared far and wide we might make a difference. At a minimum I will have something to share in my frequent Facebook battles against the army of Karen’s.

It is turning into quite a challenge and with Google doing it’s best to bury results I thought this might be an opportunity for us Cats to go against our nature and work collaboratively.

I am asking for you to leave in the comments any links and dates that would be relevant to the task ahead. In particular I am looking for:

  • studies undertaken
  • comments from prominent people
  • any expert testimonial in front of governing bodies
  • creation of doctor/expert political groups on the topic
  • real world examples of the use of ivermectin and the results (which is surprisingly difficult)
  • anything else you may feel is relevant
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137 Responses to Catallaxy crowdsource – Ivermectin

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  1. Bruce of Newcastle says:
    August 6, 2021 at 6:22 am

    I linked this one yesterday on the OT:

    Double-Blind Ivermectin Study Reveals COVID Patients Recover More Quickly, Are Less Infectious (4 Aug)

    A double-blind Israeli study has concluded that Ivermectin, an inexpensive anti-parasitic widely used since 1981, reduces both the duration and infectiousness of Covid-19, according to the Jerusalem Post.
    …
    “Our study shows first and foremost that ivermectin has antiviral activity,” said Schwartz, adding “It also shows that there is almost a 100% chance that a person will be noninfectious in four to six days, which could lead to shortening isolation time for these people. This could have a huge economic and social impact.”

    The study, which appeared on the MedRxiv preprint server and has not yet been peer-reviewed. That said, Schwartz pointed out that similar studies – ‘though not all of them conducted to the same double-blind and placebo standards as his’ – also showed favorable results for the drug.

    No doubt the Israeli medical scientists will be pilloried, but this result is in keeping with others I’ve seen, plus experience in countries like India.


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  2. Bruce of Newcastle says:
    August 6, 2021 at 6:27 am

    While I’m here I’ll add two that I have bookmarked and another one I saw some weeks ago.

    Ivermectin docks to the SARS-CoV-2 spike receptor-binding domain attached to ACE2 (June 2020)

    It’s a binding site modelling study, but it is a formal scientific paper, and it is useful to demonstrate why ivermectin works: by stuffing up the spike protein binding to the ACE2 receptor.


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  3. Bruce of Newcastle says:
    August 6, 2021 at 6:30 am

    And from Jo Nova last week:

    The battle worth fighting for: Let us and our doctors choose what medicine we take (30 Jul)

    In it you’ll find a link to a number of articles, especially one called ” The Ivermectin Review: showing how it may prevent 86% of Covid cases.” There’s also a useful link to Greg Hunt saying that GPs can prescribe ivermectin off-label, which is useful for an appeal to authority.


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  4. Bruce of Newcastle says:
    August 6, 2021 at 7:02 am

    And the fourth:

    Study reveals characteristics of SARS-CoV-2 spike protein (29 Jul)

    Dutch’s team also examined the role of key host factors in cell-to-cell fusion. In addition to binding the virus to target cells, the spike protein can cause fusion between the cell it is made in and a neighboring cell, an effect seen in the lungs of COVID-19 patients.

    Dutch says there has been relatively little research done on the spike protein’s cell-to-cell fusion or stability, so the study will contribute to giving researchers a full picture of how the proteins are made and how they function.

    This one isn’t about ivermectin, but is about why expression of the spike protein on the surfaces of cells due to the mRNA vaccines can have damaging effects – especially clot formation. The spike protien binds with an ACE2 receptor in a passing blood cell and causes the two cells to fuse.

    The Noavax vaccine is probably better since it is apparently a nanoparticle with spike proteins on it’s surface – much more like a killed-virus vaccine formulation. That should make clot formation much less likely.

    At the same time since ivermectin interferes with the spike protein binding to the ACE2 receptor it would suggest it would also be beneficial for preventing clotting with the Pfizer and AZ vaccines. However as the study says there’s little data on such things, and you can see why that might be the case given the enormous pressure from governments lately.


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  5. Bruce of Newcastle says:
    August 6, 2021 at 7:04 am

    I should add that Jo Nova has a number of articles on ivermectin, so it would be worth going to her site and put “ivermectin” in the search box.


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  7. Mullumhillbilly says:
    August 6, 2021 at 7:35 am

    Rebecca Weiser at the Spectator has tacked the topic well,
    https://www.spectator.com.au/author/rebecca-weisser
    I’ll add this one too, which may not turn up easily in searches…
    https://francais.rt.com/france/88707-ivermectine-reduit-gravite-infection-covid-19-selon-institut-pasteur

    First post as test for inclusion of two links…


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  8. Mullumhillbilly says:
    August 6, 2021 at 7:41 am

    Previous post with two links awaiting moderation.
    Ok one at a time then.., links to many studies
    https://c19ivermectin.com/


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  9. Mullumhillbilly says:
    August 6, 2021 at 7:44 am

    Review study … I think this includes results from an Egyptian trial that was later withdrawn…
    https://journals.lww.com/americantherapeutics/Fulltext/2021/08000/Ivermectin_for_Prevention_and_Treatment_of.7.aspx


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  10. Mullumhillbilly says:
    August 6, 2021 at 7:46 am

    A review … I think this includes results of an Egyptian trial that has been withdrawn
    https://journals.lww.com/americantherapeutics/Fulltext/2021/08000/Ivermectin_for_Prevention_and_Treatment_of.7.aspx


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  11. Mullumhillbilly says:
    August 6, 2021 at 7:53 am

    A couple of past posts not appearing… hmmm
    Don’t want to repeat them in case they appear later.
    Number four now…Mechanisms of action
    https://www.nature.com/articles/s41429-021-00430-5


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  13. Mullumhillbilly says:
    August 6, 2021 at 8:03 am

    Kory et al review
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8088823/#!po=0.420168

    The first post I made with two links is still in moderation…
    links can be found by searching for :-
    Rebecca Weiser Spectator author ( several articles)
    Pasteur Institute ivermectin


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  15. Mater says:
    August 6, 2021 at 8:16 am

    Adam,
    As per the other thread, I was looking at an article which was looking at a completely different medical issue, when this caught my eye. This medical article was linked to in The Lancet. Not Ivermectin, but somewhat related to the issue.

    A 60-year-old woman from Marseille, France, with a healthy body-mass index (20 kg/m2) and no notable medical history (including no articular signs or symptoms) began to have cough with unusual asthenia, myalgia, abdominal pain, and headaches on April 27, 2020, when the COVID-19 case rate was very high in France. On May 1, 2020, she consulted the University Hospital for Infectious Diseases in Marseille. An RT-PCR for SARS- CoV-2 was positive, and a chest CT scan showed the presence of a nodular condensation with a frosted glass aspect, and essentially subpleural involvement, sup- porting a diagnosis of a mild SARS-CoV-2 infection. The patient was treated with hydroxychloroquine and azithromycin for 5 days and effizinc (zinc gluconate) for 10 days. Her symptoms improved in within 5–6 days, and a repeat SARS-CoV-2 PCR test (done 11 days after the first symptoms) was negative.

    https://www.thelancet.com/pdfs/journals/lanrhe/PIIS2665-9913(20)30396-9.pdf
    Second page, third paragraph.


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  24. It's Remarkable says:
    August 6, 2021 at 8:50 am

    Thanks Adam, both for the site and the interest in Ivermectin.

    I have been reading about treatments for Covid, like many I suspect for some time. Both HCQ and Ivermectin.

    I note you have several providing links to Dr Pierre Kory and the FLCCC site – there will be good links from there to plenty of material of value.

    I have noted the work of Prof. Thomas Borody, an Australian working in Melbourne. Some links are below, many are articles or opinion pieces, though will likely have some links worth a look, and there are some more technical, also with good links.

    https://www.covid-19forum.org/index.php?topic=456.0

    https://www.nasdaq.com/press-release/ivermectin-triple-therapy-protocol-for-covid-19-released-to-australian-gps-for

    https://travag.blog/2020/09/05/proven-effective-triple-therapy-ivermectin-zinc-and-doxycycline/

    https://wentworthreport.com/2021/01/30/australian-professor-thomas-borody-ivermectin-amazingly-successful-in-killing-coronavirus/

    https://gumshoenews.com/2020/08/18/australian-professor-thomas-borody-ivermectin-amazingly-successful-in-killing-coronavirus/

    https://www.medrxiv.org/content/10.1101/2021.07.06.21259924v1


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  26. stackja says:
    August 6, 2021 at 9:34 am

    politichix says:
    August 6, 2021 at 8:04 am

    Yes!

    Front Line COVID-19 Critical Care Alliance

    Lifesaving protocols for the prevention and treatment of COVID-19

    Defeating the Delta Variant.
    The Latest Results of Ivermectin’s Success in Treating Outbreaks of COVID-19


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  27. stackja says:
    August 6, 2021 at 9:37 am

    politichix says:
    August 6, 2021 at 8:04 am
    Pierre Kory’s site – lots of info and references

    Yes

    Front Line COVID-19 Critical Care Alliance
    Front Line COVID-19 Critical Care Alliance


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  28. Katzenjammer says:
    August 6, 2021 at 9:44 am

    There is indeed firm evidence supported by numerous published studies that triple therapies based on hydroxychloroquine or ivermectin can be effective treatments when used early and there should be no prescribing restrictions on doctors for use of these long-established and safe drugs.

    https://www.spectator.com.au/2021/07/lockdown-needs-a-smackdown/
    Third last paragraph

    Dr David Adler, former Australian Medical Association deputy medical secretary.


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  29. E.J. says:
    August 6, 2021 at 9:53 am

    Very powerful ..gives the full message that Ivermectin is important
    https://www.youtube.com/watch?v=5PyQmRMAMH4


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  32. Rorschach says:
    August 6, 2021 at 10:00 am

    Dr Campbell on Ivermectin meta-analysis from 17 June [American Journal of Therapeutics]

    https://www.youtube.com/watch?v=3j7am9kjMrk


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  33. Rorschach says:
    August 6, 2021 at 10:11 am

    Dr Campbell on an Ivermectin prophylactic study from India “Prophylactic role of Ivermectin in SARS-COV-2 infection among healthcare workers” [All India Institute of Medical Sciences]

    https://www.youtube.com/watch?v=XYv30g7TKVM


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  34. John Smith101 says:
    August 6, 2021 at 10:13 am

    Ivermectin Triple Therapy Protocol for COVID-19 released to Australian GPs as treatment for Infected Elderly, Frontline Workers
    https://tinyurl.com/yh3zodh6


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  35. John Smith101 says:
    August 6, 2021 at 10:15 am

    Ivermectin for Prevention and Treatment of COVID-19 Infection: A Systematic Review, Meta-analysis, and Trial Sequential Analysis to Inform Clinical Guidelines
    Conclusions: 
    Moderate-certainty evidence finds that large reductions in COVID-19 deaths are possible using ivermectin. Using ivermectin early in the clinical course may reduce numbers progressing to severe disease. The apparent safety and low cost suggest that ivermectin is likely to have a significant impact on the SARS-CoV-2 pandemic globally.
    Source: https://journals.lww.com/americantherapeutics/Abstract/9000/Ivermectin_for_Prevention_and_Treatment_of.98040.aspx
    Also see: https://www.qld.gov.au/health/conditions/health-alerts/coronavirus-covid-19/current-status/public-health-directions/prescribing,-dispensing-or-supply-of-hydroxychloroquine-direction
    &
    https://www.health.qld.gov.au/system-governance/legislation/cho-public-health-directions-under-expanded-public-health-act-powers/prescribing-dispensing-or-supply-of-hydroxychloroquine-direction


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  36. Rorschach says:
    August 6, 2021 at 10:16 am

    Note that there have been papers withdrawn … however – most don’t challenge the findings, but on the basis of plagiarism.

    See for example:

    https://www.nature.com/articles/d41586-021-02081-w

    I just note – that a lot of these studies are by non english speaking scientists that have to write in english. and whilst skirting plagiarism if not directly acknowledged, coping of “boilerplate” and slight manipulation to get concepts across is the norm:

    The paper was “withdrawn from the Research Square platform without informing or asking me”, Elgazzar wrote in an e-mail to Nature. He defended the paper, and said of the plagiarism allegations that “often phrases or sentences are commonly used and referenced” when researchers read one another’s papers.


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  37. OldOzzie says:
    August 6, 2021 at 10:45 am

    July 21, 2021

    FIND A DOCTOR WHO WILL PRESCRIBE IVERMECTIN, HYDROXYCHLOROQUINE AND EARLY OUTPATIENT TREATMENTS FOR COVID-19 (IN VARIOUS COUNTRIES)
    Treatment should start based on clinical suspicion as soon as possible, preferably within the first 3 days of symptoms. Perform PCR testing, but do not withhold treatment pending results.

    Note: IVM = Ivermectin

    See the directory of professionals in various countries below.
    Global Directory of Doctors (by Country) Prescribing Effective Outpatient COVID-19 Therapy

    AUSTRALIA (Australian doctors who will prescribe ivermectin)
    The Centre for Digestive Diseases (IVM) 2 9713 4011 GP@CDD.com.au referrals

    Dr. Mark Hobart (IVM) 3 9311 5977

    Dr. Peter Lewis (IVM) 3 9822 9996

    Dr. Shashikanth Manikappa (IVM) 3 8768 1200

    Professor Thomas Borody MB, BS, BSc(Med), MD, PhD, DSc, FRACP, FACP, FACG,
    AGAF, FRS(N) said:

    “The three medications are on chemist shelves right now. GPs can email
    GP@CDD.com.au to obtain the dosing protocol and COVID-19 treatment information
    for their patients.


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  38. Rorschach says:
    August 6, 2021 at 10:52 am

    India is are really interesting example. In May/June there was a “massive” spike of the “Indian” (now Delta) COVID variant… All over the news with massive numbers infected and dying.

    A couple of Indian States started using ivermectin as prophylaxis – hence all the indian studies – and the severity of the infections reduced. The WHO issued a guidance that ivermectin should not be used and so it happened. The severity and death rate spiked up.

    At this point, ivermectin use was re-instated and the infection severity dropped and no one hears about india any more…

    The indian bar association has censured WHO and its scientists for “running a disinformation campaign against Ivermectin”

    https://healthpolicy-watch.news/indian-bar-association-rebukes-who-chief-scientist-over-whos-ivermectin-guidelines-for-covid-treatment/


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  39. Old bloke says:
    August 6, 2021 at 11:07 am

    “Lab experiments show anti-parasitic drug, Ivermectin, eliminates SARS-CoV-2 in cells in 48 hours”

    https://www.monash.edu/news/articles/coronavirus-fight-possible-covid-19-drug-identified-by-scientists


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  40. Old bloke says:
    August 6, 2021 at 11:19 am

    “The FDA-approved drug ivermectin inhibits the replication of SARS-CoV-2 in vitro”

    https://www.sciencedirect.com/science/article/pii/S0166354220302011?via%3Dihub


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  41. Rorschach says:
    August 6, 2021 at 11:22 am

    Old Bloke: Yes … great link. Shows that prophylactic treatments were considered and looked at very early. Literally millions have died since that study has been published!

    IF ivermectin etc is proved to be efficacious – there should be war crimes / genocide type trials on WHO/CDC, big pharma and all the Govt Types going along with this simply for political advantage. [I know – I know … in my dreams]


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  43. John A says:
    August 6, 2021 at 11:33 am

    And here is one I visited from Cats-1 some time ago:

    https://prwire.com.au/print/gps-start-prescribing-low-dose-ivermectin-triple-therapy-for-covid-19

    In Sydney.

    Also related but about HCQ

    Walter & Eliza Hall Institute Covid-Shield study:
    https://wehi.edu.au/covid-shield-faqs


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  44. Steve of kenmore says:
    August 6, 2021 at 11:39 am

    In Mar 2020, Qld government banned the use by doctors of Invermectin and HCQ.


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  45. Old bloke says:
    August 6, 2021 at 11:41 am

    “Rorschach says:
    August 6, 2021 at 11:22 am

    Old Bloke: Yes … great link. Shows that prophylactic treatments were considered and looked at very early. Literally millions have died since that study has been published!”

    ——————————————————————————————

    In April last year, when the efficacy of Ivermectin was known, the scientist were talking about manufacturing a combination of Ivermectin, some other component (can’t recall what that was), and a low dosage antibiotic to clean up the damage wrought by Covid-19 in blister packs.

    Cheap as chips to mass manufacture, they could have been over the counter pharmaceuticals in your local chemist shop well over a year ago. We could have been shipping them all over the world and been good neighbours to the Indonesians and the Pacific Islanders.

    Think of that, April last year, how much unnecessary death and suffering has happened since then.

    How many have needlessly died from Covid-19?
    How many have died or been permanently injured with the “vaccines”?
    How many have died due to not receiving essential surgery?
    How many people have lost their businesses and livelihoods?
    How many broken marriages and suicides?
    How many shattered plans and financial troubles?


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  46. Rorschach says:
    August 6, 2021 at 11:44 am

    Sensational resource Vicki!


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  47. Rorschach says:
    August 6, 2021 at 11:52 am

    In Mar 2020, Qld government banned the use by doctors of Invermectin and HCQ.

    I fail to understand why? Ivermectin has been around for decades, been used for extended courses and has saved millions. From 1997:

    https://www.nps.org.au/australian-prescriber/articles/ivermectin-1

    The worst side effects are mostly associated with the treated for parasite dying.


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  48. Rorschach says:
    August 6, 2021 at 11:56 am

    How many have needlessly died from Covid-19?
    How many have died or been permanently injured with the “vaccines”?
    How many have died due to not receiving essential surgery?
    How many people have lost their businesses and livelihoods?
    How many broken marriages and suicides?
    How many shattered plans and financial troubles?

    Yes … but our shareholders’ got a bonus. AND we got rid of “orange man bad”.


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  49. mem says:
    August 6, 2021 at 12:11 pm

    Can I suggest that these references and all the articles be printed off and saved in hard copy and/or copied and saved separately, as links to the material, or the material itself, are being disappeared at an alarming rate.


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  50. C.L. says:
    August 6, 2021 at 12:14 pm

    Very interesting thoughts from Dr Elizabeth Lee Vliet – including re hydroxychloroquine and ivermectin.

    I say that as somebody who is no more an ivermectin-ist than I am a ‘vaccination’ zombie.


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